The brainstem

The brainstem [32, 38] is an anatomical structure of the brain that connects various elements of the nervous system: the cerebrum, cerebellum, and spinal cord. It plays a vital role [32, 41, 46] due to the essential functions regulated by its nuclei [1] , including respiration and heart rate. It is also a transition zone for sensory and motor pathways, as well as a center for pain control [47, 48]. Furthermore, it serves as the site of emergence [41] of the majority of the cranial nerves [64].

It is divided into three sections [36] , which are, from top to bottom: the midbrain (mesencephalon) [49] , the pons [181] , and the medulla oblongata [72].

The midbrain :

The midbrain (or mesencephalon [38] ) is the part of the brainstem directly connected to the brain via the cerebral peduncles [38]. Behind these lies the tegmentum [49, 50, 51] , which contains the aqueduct of Sylvius [41, 43, 72] ; the latter connects the third ventricle to the fourth ventricle. Posteriorly, the midbrain contains the corpora quadrigemina [226] (tectum [39] ), which are essential for functions such as vision and hearing.

The Pons :

The pons (or pons Varolii [38] ) is the intermediate part of the brainstem. It plays an important role in motor control, particularly as a relay station between the cerebrum and the cerebellum [52] ; it also contributes to autonomic functions and facial sensation (it is at this level that the nucleus and the emergence of the trigeminal nerve are located [116] ). The pons is connected to the cerebellum by a pair of middle cerebellar peduncles [64] and forms the anterior surface (or floor) of the fourth ventricle [64].

The medulla oblongata :

The medulla (or myelencephalon [38] ) is the part of the brainstem that is continuous with the spinal cord below. It contains the olivary bodies [32] as well as the medullary pyramids [119] (structures through which the corticospinal fibers [39] of the pyramidal tract [179, 227] pass).

The medulla, or medulla oblongata [73] , contains vital autonomic control centers such as the respiratory centers [119]. It ends downward at the pyramidal decussation [5, 40] , a zone where the fibers of the corticospinal tract cross.